Blocking Bone Loss with L-BAIBA

Mark W Hamrick; Meghan Elizabeth McGee Lawrence

doi:10.1016/j.tem.2018.03.005

Blocking Bone Loss with L-BAIBA

Mark W Hamrick, Meghan Elizabeth McGee Lawrence

Cellular Biology and Anatomy

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

Osteocytes are cells nested within the mineralized bone matrix that play a key role in maintaining bone mass. New findings in Cell Reports show that β-aminoisobutyric acid (L-BAIBA), a metabolite secreted from muscle, promotes osteocyte survival under oxidative stress. This discovery reveals a novel mechanism linking muscle activity to skeletal health.

Original language	English (US)
Pages (from-to)	284-286
Number of pages	3
Journal	Trends in Endocrinology and Metabolism
Volume	29
Issue number	5
DOIs	https://doi.org/10.1016/j.tem.2018.03.005
State	Published - May 2018

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.tem.2018.03.005

Cite this

@article{32490a895fb44ee688c55932b724c934,

title = "Blocking Bone Loss with L-BAIBA",

abstract = "Osteocytes are cells nested within the mineralized bone matrix that play a key role in maintaining bone mass. New findings in Cell Reports show that β-aminoisobutyric acid (L-BAIBA), a metabolite secreted from muscle, promotes osteocyte survival under oxidative stress. This discovery reveals a novel mechanism linking muscle activity to skeletal health.",

author = "Hamrick, {Mark W} and {McGee Lawrence}, {Meghan Elizabeth}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Ltd",

year = "2018",

month = may,

doi = "10.1016/j.tem.2018.03.005",

language = "English (US)",

volume = "29",

pages = "284--286",

journal = "Trends in Endocrinology and Metabolism",

issn = "1043-2760",

publisher = "Elsevier Inc.",

number = "5",

}

TY - JOUR

T1 - Blocking Bone Loss with L-BAIBA

AU - Hamrick, Mark W

AU - McGee Lawrence, Meghan Elizabeth

PY - 2018/5

Y1 - 2018/5

N2 - Osteocytes are cells nested within the mineralized bone matrix that play a key role in maintaining bone mass. New findings in Cell Reports show that β-aminoisobutyric acid (L-BAIBA), a metabolite secreted from muscle, promotes osteocyte survival under oxidative stress. This discovery reveals a novel mechanism linking muscle activity to skeletal health.

AB - Osteocytes are cells nested within the mineralized bone matrix that play a key role in maintaining bone mass. New findings in Cell Reports show that β-aminoisobutyric acid (L-BAIBA), a metabolite secreted from muscle, promotes osteocyte survival under oxidative stress. This discovery reveals a novel mechanism linking muscle activity to skeletal health.

UR - http://www.scopus.com/inward/record.url?scp=85044305349&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85044305349&partnerID=8YFLogxK

U2 - 10.1016/j.tem.2018.03.005

DO - 10.1016/j.tem.2018.03.005

M3 - Short survey

C2 - 29573947

AN - SCOPUS:85044305349

SN - 1043-2760

VL - 29

SP - 284

EP - 286

JO - Trends in Endocrinology and Metabolism

JF - Trends in Endocrinology and Metabolism

IS - 5

ER -

Blocking Bone Loss with L-BAIBA

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this