Calcium and vitamin D requirements of enterally fed preterm infants

Steven A. Abrams, Jatinder J.S. Bhatia, Mark R. Corkins, Sarah D. De Ferranti, Neville H. Golden, Janet Silverstein, Laurence Grummer-Strawn, Van Hubbard, Valerie Marchand, Benson M. Silverman, Valery Soto, Debra L. Burrowes

Research output: Contribution to journalArticlepeer-review

208 Scopus citations


Bone health is a critical concern in managing preterm infants. Key nutrients of importance are calcium, vitamin D, and phosphorus. Although human milk is critical for the health of preterm infants, it is low in these nutrients relative to the needs of the infants during growth. Strategies should be in place to fortify human milk for preterm infants with birth weight <1800 to 2000 g and to ensure adequate mineral intake during hospitalization and after hospital discharge. Biochemical monitoring of very low birth weight infants should be performed during their hospitalization. Vitamin D should be provided at 200 to 400 IU/day both during hospitalization and after discharge from the hospital. Infants with radiologic evidence of rickets should have efforts made to maximize calcium and phosphorus intake by using available commercial products and, if needed, direct supplementation with these minerals.

Original languageEnglish (US)
Pages (from-to)e1676-e1683
Issue number5
StatePublished - May 2013
Externally publishedYes


  • Calcium
  • Human milk
  • Nutrient intake
  • Phosphorous
  • Preterm infants
  • Vitamin D

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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