TY - JOUR
T1 - Clinical evaluation of a 3% hydrogen peroxide tooth-whitening Gel
AU - Myers, Michael L.
AU - Browning, William D.
AU - Downey, Mary C.
AU - Hackman, Steven T.
PY - 2003/1/1
Y1 - 2003/1/1
N2 - Purpose: The purpose of this randomized double-blind investigation was to clinically evaluate the effectiveness of a commercially available 3% hydrogen peroxide tooth-whitening material (ADS Tooth Whitening Gel, Applied Dental Sciences, Inc., Lee, MA). The material was used over 2 weeks in a dentist-supervised, patient-applied application. Materials and Methods: The evaluation was carried out in accordance with American Dental Association (ADA) Council on Scientific Affairs Acceptance Program Guidelines for Home-Use Tooth Whitening Products (May 1998). Sixty-five participants were randomized into two groups (active and placebo) for a double-blind, placebo-controlled study. A custom application tray, scalloped without reservoirs, was fabricated for each participant. Tooth shades were documented by matching with the Vita shade guide ordered according to value and assigned a numeric ranking from 1 to 16, darkest to lightest. Participants were supplied with the treatment solutions to use in the application tray. Duration of active treatment was 30 minutes 3 times a day for 2 weeks. Participants were evaluated at baseline, 1 week and 2 weeks treatment, and 12 and 26 weeks post-treatment. The statistical analysis used at each time point to determine the difference between the active and placebo groups based on the change in value was the two-sample t-test. Plaque and soft tissue indices were also recorded. Results: The teeth treated with 3% hydrogen peroxide were significantly lighter at 2, 12, and 26 weeks (p ≤ .0140, .0004, and .0001, respectively) compared with the placebo group. The mean shade change was 4.2 Vita shade tabs at 2 weeks. At 26 weeks (6 months), the degree of whitening was 4.1 tabs.
AB - Purpose: The purpose of this randomized double-blind investigation was to clinically evaluate the effectiveness of a commercially available 3% hydrogen peroxide tooth-whitening material (ADS Tooth Whitening Gel, Applied Dental Sciences, Inc., Lee, MA). The material was used over 2 weeks in a dentist-supervised, patient-applied application. Materials and Methods: The evaluation was carried out in accordance with American Dental Association (ADA) Council on Scientific Affairs Acceptance Program Guidelines for Home-Use Tooth Whitening Products (May 1998). Sixty-five participants were randomized into two groups (active and placebo) for a double-blind, placebo-controlled study. A custom application tray, scalloped without reservoirs, was fabricated for each participant. Tooth shades were documented by matching with the Vita shade guide ordered according to value and assigned a numeric ranking from 1 to 16, darkest to lightest. Participants were supplied with the treatment solutions to use in the application tray. Duration of active treatment was 30 minutes 3 times a day for 2 weeks. Participants were evaluated at baseline, 1 week and 2 weeks treatment, and 12 and 26 weeks post-treatment. The statistical analysis used at each time point to determine the difference between the active and placebo groups based on the change in value was the two-sample t-test. Plaque and soft tissue indices were also recorded. Results: The teeth treated with 3% hydrogen peroxide were significantly lighter at 2, 12, and 26 weeks (p ≤ .0140, .0004, and .0001, respectively) compared with the placebo group. The mean shade change was 4.2 Vita shade tabs at 2 weeks. At 26 weeks (6 months), the degree of whitening was 4.1 tabs.
UR - http://www.scopus.com/inward/record.url?scp=0038654169&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0038654169&partnerID=8YFLogxK
U2 - 10.1111/j.1708-8240.2003.tb00282.x
DO - 10.1111/j.1708-8240.2003.tb00282.x
M3 - Article
C2 - 12638773
AN - SCOPUS:0038654169
SN - 1496-4155
VL - 15
SP - 50
EP - 56
JO - Journal of Esthetic and Restorative Dentistry
JF - Journal of Esthetic and Restorative Dentistry
IS - 1
ER -