COPD may increase the incidence of refractory supraventricular arrhythmias following pulmonary resection for non-small cell lung cancer.

Y Sekine, K A Kesler, M Behnia, J Brooks-Brunn, E Sekine, J W Brown

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Purpose: This study investigated the association of COPD and postoperative cardiac arrhythmias, specifically supraventricular tachycardia (SVT), as well as mortality in patients undergoing pulmonary resection for non-small cell lung cancer (NSCLC).; Methods: A retrospective chart review of 244 patients who had undergone lung resection for NSCLC at Indiana University Hospital between 1992 and 1997 was undertaken. COPD, which was defined as an FEV(1) of <or = 70% predicted and an FEV(1)/FVC ratio of <or = 70% based on the results of a preoperative pulmonary function test (PFT), was diagnosed in 78 of the 244 patients (COPD group). In the remaining 166 patients, the results of preoperative PFTs did not meet these criteria (non-COPD group). Both groups were otherwise well-matched with respect to multiple variables, including age, comorbid conditions, extent of pulmonary resection, and final pathologic stage. The incidence of cardiac arrhythmias and operative mortality were compared betw
Original languageUndefined
Pages (from-to)1783 - 1790
Issue number6
StatePublished - 2001


  • Pneumonectomy*, Carcinoma, Non-Small-Cell Lung/*surgery, Lung Neoplasms/*surgery, Postoperative Complications/*etiology, Pulmonary Disease, Chronic Obstructive/*complications, Tachycardia, Supraventricular/*etiology, Aged, Anti-Arrhythmia Agents/administration & dosage, Atrial Fibrillation/etiology, Atrial Fibrillation/mortality, Carcinoma, Non-Small-Cell Lung/mortality, Cause of Death, Digoxin/administration & dosage, Female, Forced Expiratory Volume, Hospital Mortality, Humans, Lung Neoplasms/mortality, Male, Middle Aged, Postoperative Complications/mortality, Pulmonary Disease, Chronic Obstructive/mortality, Pulmonary Disease, Chronic Obstructive/surgery, Risk Factors, Survival Rate, Tachycardia, Supraventricular/mortality, Vital Capacity

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