TY - JOUR
T1 - Cytoplasmic and nuclear inheritance of resistance to alkylguanidines and ethidium bromide in a petite-negative yeast
AU - Brunner, Aurora
AU - Mas, J.
AU - Celis, E.
AU - Mattoon, J. R.
N1 - Funding Information:
This work was supported from the Organization
PY - 1973/7/17
Y1 - 1973/7/17
N2 - Mutants of the petite-negative yeast, Kluyveromyceslactis, resistant to the inhibitors of oxidative phosphorylation, decamethylenediguanidine and octylguanidine were isolated from medium containing ethidium bromide. All mutants were resistant to ethidium bromide; some mutants were resistant to both alkylguanidines, some to one, others to neither. Both nuclear and cytoplasmic inheritance of resistance to decamethylenediguanidine and ethidium bromide was demonstrated by tetrad analysis.
AB - Mutants of the petite-negative yeast, Kluyveromyceslactis, resistant to the inhibitors of oxidative phosphorylation, decamethylenediguanidine and octylguanidine were isolated from medium containing ethidium bromide. All mutants were resistant to ethidium bromide; some mutants were resistant to both alkylguanidines, some to one, others to neither. Both nuclear and cytoplasmic inheritance of resistance to decamethylenediguanidine and ethidium bromide was demonstrated by tetrad analysis.
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U2 - 10.1016/0006-291X(73)90709-2
DO - 10.1016/0006-291X(73)90709-2
M3 - Article
C2 - 4716992
AN - SCOPUS:0015833588
SN - 0006-291X
VL - 53
SP - 638
EP - 644
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 2
ER -