Design, synthesis and biological activities of quinazoline containing sorafenib analogs as antitumor agents

Keyphrases

• Cytotoxicity 100%
• Biological Activity 100%
• Antitumor Agents 100%
• Quinazoline 100%
• Design Activity 100%
• Sorafenib Analogs 100%
• Antiproliferative Activity 50%
• Phosphorylation 50%
• C-Raf 50%
• ERK2 50%
• Antitumor Activity 50%
• MEK1 50%
• MTT Assay 50%
• B16 Melanoma 50%
• Xenograft Model 50%
• Inhibitory Activity 50%
• Sorafenib 50%
• HCT116 50%
• Synthesized Compounds 50%
• Quinazoline Moiety 50%
• Melanoma Xenografts 50%
• Sorafenib Derivatives 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Anticarcinogen 100%
• Biological Activity 100%
• Sorafenib 100%
• Quinazoline 100%
• Cytotoxicity 66%
• Neoplasm 33%
• Mitogen Activated Protein Kinase 3 33%
• Antiproliferative Activity 33%
• Melanoma B16 33%