Immunoglobulin production by mitogen and recombinant interleukin-2-(rIL-2)-stimulated lymphocytes from IgM-deficient patients was studied. The findings were that subnormal serum IgM levels did not necessarily predict defective in vitro IgG or IgM production, lymphocytes from some IgM-deficient patients exhibited defective T cell function, and rIL-2 did not enhance defective in vitro immunoglobulin production.
|Original language||English (US)|
|Number of pages||4|
|Journal||Annals of Allergy|
|State||Published - Dec 1 1988|
ASJC Scopus subject areas
- Immunology and Allergy