Effect of marine glycosides on adenosinetriphosphatase activity

Boris A Gorshkov, I. A. Gorshkova, V. A. Stonik, G. B. Elyakov

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Marine glycosides from the sea cucumbers Actinopyga agassizi, Holothuria atra, Bohadschia argus, Cucumaria fraudatrix, Astichopus multifidus and Thelenota ananas inhibit both Na+-K+ ATPase and Mg2+-ATPase of rat brain in vitro. The glycoside-cholesterol complex of these compounds does not influence ATPase activity. Asterosaponins from starfishes Linckia guildingi and Linckia laevigata possess a slight inhibiting effect. The triterpene glycosides from sea cucumbers are more powerful inhibitors than steroidal glycosides from starfishes.

Original languageEnglish (US)
Pages (from-to)655-658
Number of pages4
Issue number3
StatePublished - 1982

ASJC Scopus subject areas

  • Toxicology


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