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Enhancement of dorsal hippocampal activity by knockdown of hcn1 channels leads to anxiolytic- and antidepressant-like behaviors
Chung Sub Kim
, Payne Y. Chang
, Daniel Johnston
Research output
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Contribution to journal
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Article
›
peer-review
136
Scopus citations
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Dive into the research topics of 'Enhancement of dorsal hippocampal activity by knockdown of hcn1 channels leads to anxiolytic- and antidepressant-like behaviors'. Together they form a unique fingerprint.
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Keyphrases
Antidepressants
100%
Knockdown
100%
Anxiolytic
100%
Hippocampal Activity
100%
HCN1
100%
Brain Regions
40%
Knock-in Mouse Model
40%
Hippocampal CA1 Region
40%
Lentiviral shRNA
40%
HCN Channels
40%
Signaling Pathway
20%
Physiological Changes
20%
Hippocampus
20%
Affective Disorders
20%
Anxiety Disorders
20%
Mammalian Target of Rapamycin (mTOR)
20%
Cellular Excitability
20%
Anxiolytic Activity
20%
Depression Disorder
20%
TRIP8b
20%
HCN2
20%
Neuroscience
Antidepressant
100%
Behavior (Neuroscience)
100%
HCN1
100%
Small Hairpin RNA
40%
Cell Signaling
20%
Hippocampus
20%
Mood Disorder
20%
Brain-Derived Neurotrophic Factor
20%
Excitability
20%
HCN Channel
20%
mTOR Signaling
20%
HCN2
20%