Factors affecting sleep quality in patients with psoriasis

Smitha Gowda, Orin M. Goldblum, W. Vaughn McCall, Steven R. Feldman

Research output: Contribution to journalReview articlepeer-review

88 Scopus citations


Poor sleep quality adversely affects quality of life in patients with psoriasis. However, the factors impairing sleep in these patients have not been well described. We reviewed the available literature linking sleep quality and psoriasis to elucidate factors that interfere with sleep. Pruritus, depression, pain, and obstructive sleep apnea may be likely sources of sleep impairment in patients with psoriasis. Fatigue resulting from sleep interference may also be implicated in this relationship. Pruritus, depression, and pain interfere with sleep quality by increasing nocturnal awakenings and sleep fragmentation. Obstructive sleep apnea may occur in a greater percentage of patients with psoriasis than control populations. Factors associated with psoriasis appear to have similarities in their cytokine and neuropeptide profiles. Moreover, these variables are complex and interconnected. Further study and awareness of potential factors impacting sleep in patients with psoriasis may provide new avenues for treatment of recalcitrant disease.

Original languageEnglish (US)
Pages (from-to)114-123
Number of pages10
JournalJournal of the American Academy of Dermatology
Issue number1
StatePublished - Jul 2010
Externally publishedYes


  • dermatology
  • itch
  • psoriasis
  • sleep

ASJC Scopus subject areas

  • Dermatology


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