Feasibility study of lactate imaging of head and neck tumors

E. Adalsteinsson; D. M. Spielman; J. M. Pauly; D. J. Terris; G. Sommer; A. Macovski

doi:10.1002/(SICI)1099-1492(1998110)11:7<360::AID-NBM518>3.0.CO;2-P

Feasibility study of lactate imaging of head and neck tumors

E. Adalsteinsson, D. M. Spielman, J. M. Pauly, D. J. Terris, G. Sommer, A. Macovski

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

A proton spectroscopic imaging sequence was used to investigate the feasibility of lactate imaging in head and neck tumors. The sequence employs a two-shot lactate editing method with inversion recoverY for additional lipid suppression, and a restricted field of view to suppress motion artifacts. Variations in acquisition parameters and two different receive coils were investigated on twelve patients. Elevated lactate was detected in three patients, no lactate was observed in seven patients, and two studies were inconclusive because of severe motion or inhomogeneity artifacts. Best results were obtained with an anterior/posterior neck coil at a 288 ms echo time (TE).

Original language	English (US)
Pages (from-to)	360-369
Number of pages	10
Journal	NMR in Biomedicine
Volume	11
Issue number	7
DOIs	https://doi.org/10.1002/(SICI)1099-1492(1998110)11:7<360::AID-NBM518>3.0.CO;2-P
State	Published - Nov 1998
Externally published	Yes

Keywords

Head and neck tumors
In vivo lactate
Lactic acid
Spectroscopic imaging
Squamous cell carcinoma

ASJC Scopus subject areas

Molecular Medicine
Radiology Nuclear Medicine and imaging
Spectroscopy

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10.1002/(SICI)1099-1492(1998110)11:7<360::AID-NBM518>3.0.CO;2-P

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title = "Feasibility study of lactate imaging of head and neck tumors",

abstract = "A proton spectroscopic imaging sequence was used to investigate the feasibility of lactate imaging in head and neck tumors. The sequence employs a two-shot lactate editing method with inversion recoverY for additional lipid suppression, and a restricted field of view to suppress motion artifacts. Variations in acquisition parameters and two different receive coils were investigated on twelve patients. Elevated lactate was detected in three patients, no lactate was observed in seven patients, and two studies were inconclusive because of severe motion or inhomogeneity artifacts. Best results were obtained with an anterior/posterior neck coil at a 288 ms echo time (TE).",

keywords = "Head and neck tumors, In vivo lactate, Lactic acid, Spectroscopic imaging, Squamous cell carcinoma",

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year = "1998",

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AU - Adalsteinsson, E.

AU - Spielman, D. M.

AU - Pauly, J. M.

AU - Terris, D. J.

AU - Sommer, G.

AU - Macovski, A.

PY - 1998/11

Y1 - 1998/11

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AB - A proton spectroscopic imaging sequence was used to investigate the feasibility of lactate imaging in head and neck tumors. The sequence employs a two-shot lactate editing method with inversion recoverY for additional lipid suppression, and a restricted field of view to suppress motion artifacts. Variations in acquisition parameters and two different receive coils were investigated on twelve patients. Elevated lactate was detected in three patients, no lactate was observed in seven patients, and two studies were inconclusive because of severe motion or inhomogeneity artifacts. Best results were obtained with an anterior/posterior neck coil at a 288 ms echo time (TE).

KW - Head and neck tumors

KW - In vivo lactate

KW - Lactic acid

KW - Spectroscopic imaging

KW - Squamous cell carcinoma

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Feasibility study of lactate imaging of head and neck tumors

Abstract

Keywords

ASJC Scopus subject areas

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