Gynecomastia and hypertension.

L. Michael Prisant, Edward Chin

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


Palpable dense and mobile subareolar tissue in the male breast defines the presence of gynecomastia. For the hypertension specialist, breast enlargement in men provides a clue to a secondary cause of hypertension or an adverse antihypertensive drug reaction. Hyperthyroidism, chronic renal failure, adrenal hyperplasia or tumors, amphetamine, cyclosporine, and anabolic steroids are secondary causes of hypertension associated with gynecomastia. Reserpine, methyldopa, and spironolactone are older drugs associated with gynecomastia; however, calcium antagonists (more commonly), angiotensin-converting enzyme inhibitors, and alpha1 blockers may also be associated with this finding. Treatment is directed to removal of the underlying cause.

Original languageEnglish (US)
Pages (from-to)245-248
Number of pages4
JournalJournal of clinical hypertension (Greenwich, Conn.)
Issue number4
StatePublished - Apr 2005

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine


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