IgG4-related disease presenting as a solitary neck mass

Tyler McKinnon, William T. Randazzo, Brian D. Kim, Paul Biddinger, Scott Forseen

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


IgG4-related disease is a newly recognized entity associated with autoimmune conditions involving almost every organ system. It is characterized by elevated serum IgG4 as well as mass like tissue infiltration by IgG4-positive plasma cells. Imaging findings are nonspecific, vary depending on the site of disease, and include mass like enlargement of the salivary or lacrimal glands and enlarged lymph nodes. Radiographic findings often mimic malignancy, necessitating tissue sampling to confirm the diagnosis. Distinguishing IgG4-related disease from malignancy is important as IgG4 responds well to steroids and conservative management.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalJournal of Radiology Case Reports
Issue number2
StatePublished - 2015


  • Autoimmune
  • IgG4 related disease
  • Neck mass
  • Sclerosing disease

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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