Impact of COPD on pulmonary complications and on long-term survival of patients undergoing surgery for NSCLC.

Yasuo Sekine, Mehrdad Behnia, Takehiko Fujisawa

Research output: Contribution to journalArticlepeer-review

142 Scopus citations


Purpose: The purpose of our study was to determine the incidence of various types of postoperative pulmonary complications and to evaluate the impact of chronic obstructive pulmonary disease (COPD) on the long-term survival of patients with non-small cell lung cancer (NSCLC) undergoing pulmonary resection.; Methods: We performed a retrospective chart review of 244 patients who had undergone lung resection for NSCLC at Indiana University. COPD, defined as predicted forced expiratory volume in 1 s (FEV1)<or =70% and FEV1/FVC<or =70%, was determined based on preoperative pulmonary function testing in 78 of 244 patients (COPD group). The remaining 166 patients were classified as non-COPD. The incidence of postoperative complications, which included air leak of > or=10 days, atelectasis, pneumothorax, pneumonia, bronchopleural fistula, empyema, acute respiratory distress syndrome, mechanical ventilation of > or =7 days, and outpatient oxygen supplementation were compared between the two
Original languageUndefined
Pages (from-to)95 - 101
JournalLung Cancer
Issue number1
StatePublished - 2002


  • Postoperative Complications*, Carcinoma, Non-Small-Cell Lung/*surgery, Lung Neoplasms/*surgery, Pulmonary Disease, Chronic Obstructive/*complications, Aged, Carcinoma, Non-Small-Cell Lung/complications, Female, Humans, Lung Neoplasms/complications, Male, Middle Aged, Prognosis, Respiratory Function Tests, Retrospective Studies, Survival

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