Implications of left bundle branch block in patient treatment

Vineet Kumar, Rajesh Venkataraman, Wael Aljaroudi, Jose Osorio, Jaekyeong Heo, Ami E. Iskandrian, Fadi G. Hage

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations


Left bundle branch block (LBBB) causes an abnormal pattern of cardiac activation and affects regional myocardial function. Although recognition of LBBB on the surface electrocardiogram is straightforward, dissecting its effect on patient treatment and outcome can be more challenging. The altered pattern of cardiac activation in LBBB causes electrical and mechanical ventricular dyssynchrony, influences ischemia detection on the surface electrocardiogram, and affects stress testing and imaging modalities dependent on wall motion and thickening. Restoration of synchrony by biventricular pacing can improve symptoms and longevity in carefully selected patients. The diagnostic, prognostic, and therapeutic implications of LBBB across this spectrum are discussed in this review.

Original languageEnglish (US)
Pages (from-to)291-300
Number of pages10
JournalAmerican Journal of Cardiology
Issue number2
StatePublished - Jan 15 2013
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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