Inactivating Mutations in GT198 in Familial and Early-Onset Breast and Ovarian Cancers

Keyphrases

• 5′-untranslated Region (5′-UTR) 14%
• Alternative Splicing 14%
• Blood DNA 14%
• Breast Cancer 14%
• Breast Cancer Patients 28%
• Breast Cancer Susceptibility Gene 1 (BRCA1) 14%
• Cancer Families 14%
• Cancer Predisposition 14%
• Chromosome 17q21 14%
• DNA Damage 14%
• DNA Repair 28%
• Early Breast Cancer 100%
• Early Onset 14%
• Familial Breast Cancer 14%
• Familial Ovarian Cancer 14%
• Focus Formation 14%
• Gene Activation 14%
• Gene Amplification 14%
• Gene Regulating 14%
• Gene Symbols 14%
• Gene-gene 14%
• Germline mutation 28%
• Germline Variants 14%
• GT198 100%
• Homologous Recombination 14%
• Inactivating mutation 100%
• Index Patient 28%
• Nonsense mutation 14%
• Ovarian Cancer 100%
• Ovarian Cancer Patients 28%
• Protein Drug 14%
• PSMC3IP 14%
• RAD51 14%
• Receptor-mediated 14%
• Somatic mutation 42%
• Splice Junction 14%
• Steroid Receptors 14%
• Truncating mutation 14%
• Tumor 28%
• Upstream Open Reading Frame (uORF) 14%

Biochemistry, Genetics and Molecular Biology

• Allele 33%
• Alternative Splicing 33%
• BRCA1 33%
• DNA Damage 33%
• DNA Repair 66%
• Gene Activation 33%
• Gene Amplification 33%
• Germ Cell 33%
• Germline 33%
• Germline Mutation 66%
• Homologous Recombination 33%
• Nonsense Mutation 33%
• Open Reading Frame 33%
• Somatic Mutation 100%
• Steroid Hormone Receptor 33%
• Wild Type 66%

Immunology and Microbiology

• Allele 33%
• Alternative RNA Splicing 33%
• DNA Damage 33%
• DNA Repair 66%
• Gene Activation 33%
• Gene Amplification 33%
• Germline Mutation 66%
• Homologous Recombination 33%
• Nonsense Mutation 33%
• Open Reading Frame 33%
• Somatic Mutation 100%
• Wild Type 66%