Inhibition of gastric tumor growth by a novel Hsp90 inhibitor

Keyphrases

• Heat Shock Protein 90 (Hsp90) 100%
• Tumor Growth 100%
• Heat Shock Protein 90 Inhibitor 100%
• Gastric Tumor 100%
• C-Raf 60%
• BGC-823 40%
• Oncoprotein 20%
• Clinical Trials 20%
• Weight Loss 20%
• Cell Population 20%
• Tumor Cells 20%
• Chaperone Proteins 20%
• Cellular Signaling 20%
• Induced Apoptosis 20%
• Caspase-3 20%
• ERK Pathway 20%
• Normal Cell Line 20%
• Antitumor Effect 20%
• Molecular Chaperone 20%
• Resorcinol Derivatives 20%
• AKT1 20%
• Co-chaperone 20%
• Gastric Cancer 20%
• Gastric Cancer Cells 20%
• Improved Efficacy 20%
• Xenograft Mice 20%
• ATP-binding Pocket 20%
• Low Toxicity 20%
• 17-AAG 20%
• In Vitro Anticancer Activity 20%
• Cancer Cell Viability 20%
• Fluorescence Polarization Assay 20%
• Synthetic Small Molecules 20%
• Cdc37 20%
• Efficacy-toxicity 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Tumor Growth 100%
• Heat Shock Protein 90 100%
• Heat Shock Protein 90 Inhibitor 100%
• Stomach Tumor 100%
• Chaperone 40%
• Stomach Cancer 40%
• Oncoprotein 20%
• Malignant Neoplasm 20%
• Clinical Trial 20%
• Neoplasm 20%
• Normal Human 20%
• Caspase 3 20%
• Nude Mouse 20%
• Adenosine Triphosphate 20%
• Cell Viability 20%
• Resorcinol Derivative 20%
• Tanespimycin 20%
• Cell Cycle Protein 37 20%

Biochemistry, Genetics and Molecular Biology

• Tumor Progression 100%
• Heat Shock Protein 100%
• Heat Shock Protein 90 Inhibitor 100%
• Cancer Cell 40%
• Adenosine Triphosphate 20%
• Poly ADP Ribose Polymerase 20%
• Chaperone (Protein) 20%
• Signal Transduction 20%
• Clinical Trial 20%
• Caspase 3 20%
• Nude Mouse 20%
• Normal Human 20%
• Cell Viability 20%
• Co-Chaperone 20%
• Antineoplastic Activity 20%
• Small Molecule 20%
• Body Weight Loss 20%