Interaction of [³H]spiperone with rat striatal dopamine D-2 receptors: Kinetic evidence for antagonist-induced formation of ternary complex

Keyphrases

• Binding Experiment 9%
• Binding Reaction 81%
• Binding Site 18%
• Bromocriptine 18%
• D-value 9%
• D2 Receptor 9%
• Dissociation 18%
• Dissociation Constant 9%
• Dissociation Rate Constant 18%
• Dopamine 36%
• Dopamine Agonist 9%
• Dopamine D2 Receptor (DRD2) 100%
• Dose-response Curve 18%
• Equilibrium Binding 27%
• Equilibrium Data 9%
• Freeform 9%
• G Protein 54%
• Guanosine 9%
• High Affinity 27%
• Homogeneous Population 9%
• Imidodiphosphate 9%
• Inconsistency 9%
• Incubation 9%
• Infinite Dilution 9%
• Isomerization 18%
• Kinetic Data 9%
• Ligand Concentration 9%
• Ligand-receptor Binding 9%
• Low Affinity 9%
• Monophasic 9%
• Number of Binding Sites 9%
• Occupancy 9%
• Pertussis Toxin 9%
• Pseudo-first-order Rate Constant 9%
• Receptor Kinetics 100%
• Receptor Sites 9%
• Spiperone 100%
• Striatal Dopamine 100%
• Striatum 9%
• Ternary Complex 100%
• Third Component 9%

Biochemistry, Genetics and Molecular Biology

• Binding Protein 9%
• Binding Site 27%
• Bromocriptine 18%
• Dilution 9%
• Dissociation Constant 9%
• Dissociation Rate Constant 18%
• Dopamine Agonist 9%
• Dose Response 18%
• Eicosanoid Receptor 90%
• First Order Rate Constant 9%
• G Protein 45%
• Guanine 9%
• Guanosine 9%
• Isomerization 18%
• Pertussis Toxin 9%
• Spiperone 100%
• Ternary Complex 100%

Neuroscience

• Binding Site 27%
• Bromocriptine 18%
• Dopamine Agonist 9%
• Eicosanoid Receptor 90%
• Epileptic Absence 18%
• G Protein 54%
• Guanosine 9%
• Pertussis Toxin 9%
• Spiperone 100%
• Striatum 9%