Internal Ribosome Entry Site-Based Bicistronic In Situ Reporter Assays for Discovery of Transcription-Targeted Lead Compounds

Keyphrases

• In Situ 100%
• Reporter Assay 100%
• Internal Ribosome Entry Site 100%
• Site-based 100%
• Bicistronic 100%
• Endogenous Genes 66%
• Reporter Gene Expression 33%
• Cis-acting Elements 33%
• Rapid Development 33%
• Reporter Gene 33%
• Gene Locus 33%
• Eukaryotic Translation Initiation Factor 4E (eIF4E) 33%
• Reporter Gene Assay 33%
• Driving Genes 33%
• Epigenetic Environment 33%
• Orthogonal Assay 33%
• Recombinase-mediated Cassette Exchange 33%
• Chemical Response 33%
• Genome Editing 33%
• Screening Platform 33%
• Small Molecule Targets 33%
• CRISPR-Cas9 Genome Editing 33%
• Endogenous Gene Expression 33%

Biochemistry, Genetics and Molecular Biology

• Transcription 100%
• Reporter Gene 100%
• Internal Ribosome Entry Site 100%
• Gene Expression 66%
• Carcinogenesis 33%
• Gene Locus 33%
• Transgene 33%
• Small Molecule 33%
• Cis Acting Element 33%
• Genome Editing 33%
• Recombinase-Mediated Cassette Exchange 33%
• CRISPR/Cas9 33%

Immunology and Microbiology

• Reporter Gene 100%
• Internal Ribosome Entry Site 100%
• Gene Expression 66%
• Gene Locus 33%
• Transgene 33%
• Initiation Factor 4E 33%
• Cis Acting Element 33%
• CRISPR/Cas9 33%
• Gene Editing 33%