Intrathecal baclofen therapy and multiple sclerosis: outcomes and patient satisfaction.

John R. Vender, Mary Hughes, Betsy D. Hughes, Sydney Hester, Stephen Holsenback, Brenda Rosson

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


OBJECT: In this study the authors provide an assessment of intrathecal baclofen (ITB) therapy and evaluate patient outcomes and satisfaction. METHODS: Records for patients with multiple sclerosis who were selected as candidates for ITB therapy were reviewed for their response to test dose, surgical technique, surgery- and pump-related complications, and short- and long-term response to therapy. Family and caregiver assessments of the value of ITB therapy were also reviewed. CONCLUSIONS: Intrathecal baclofen therapy is safe and effective. Most patients and caregivers express satisfaction with the therapy and would recommend it to other patients. Spasm frequency appears to be the single most common variable positively affected by therapy.

Original languageEnglish (US)
Pages (from-to)e6
JournalNeurosurgical focus
Issue number2
StatePublished - 2006

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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