Abstract
N(α) -Boc-N(im) -(4-toluenesulfonyl-l-histidylbenzotriazole) enables convenient acylation of N-, O-, S-, and C-nucleophiles with no detectable racemization. We report efficient syntheses of novel histidine-containing di-, tri-, and tetra-peptides and models for the preparation of potentially biologically active histidine N-, O-, S-, and C-conjugates.
Original language | English (US) |
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Pages (from-to) | 110-7 |
Number of pages | 8 |
Journal | Journal of Peptide Science |
Volume | 19 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2013 |
Keywords
- Histidine
- Molecular Structure
- Oligopeptides
- Tosyl Compounds
- Triazoles
- Journal Article
- Research Support, Non-U.S. Gov't