Lead revision surgery for vagus nerve stimulation in epilepsy: Outcomes and efficacy

Hena Waseem; Scott J. Raffa; Selim R. Benbadis; Fernando L. Vale

doi:10.1016/j.yebeh.2013.12.002

Lead revision surgery for vagus nerve stimulation in epilepsy: Outcomes and efficacy

Hena Waseem, Scott J. Raffa, Selim R. Benbadis, Fernando L. Vale

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

We present, to our knowledge, the first published analysis of vagus nerve stimulation (VNS) lead revisions to incorporate quality of life, clinical response, and antiepileptic drug (AED) burden in postrevision clinical outcomes. Ten patients were followed and had no postoperative complications. Seven patients had improvement in quality of life, and three experienced no change. Eight patients noted a restoration of clinical response comparable with initial VNS implantation. Seven patients reported 30-60% improvement in seizure reduction, two experienced >. 60%, and one noted <. 30%. Six patients had no change in AED burden. Vagus nerve stimulation lead revision should be considered a safe option for patients with VNS lead failure and medically intractable epilepsy.

Original language	English (US)
Pages (from-to)	110-113
Number of pages	4
Journal	Epilepsy and Behavior
Volume	31
DOIs	https://doi.org/10.1016/j.yebeh.2013.12.002
State	Published - Feb 1 2014
Externally published	Yes

Keywords

Epilepsy surgery
Intractable epilepsy
Lead revision
Seizure disorder
Vagus nerve stimulation

ASJC Scopus subject areas

Neurology
Clinical Neurology
Behavioral Neuroscience

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10.1016/j.yebeh.2013.12.002

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abstract = "We present, to our knowledge, the first published analysis of vagus nerve stimulation (VNS) lead revisions to incorporate quality of life, clinical response, and antiepileptic drug (AED) burden in postrevision clinical outcomes. Ten patients were followed and had no postoperative complications. Seven patients had improvement in quality of life, and three experienced no change. Eight patients noted a restoration of clinical response comparable with initial VNS implantation. Seven patients reported 30-60% improvement in seizure reduction, two experienced >. 60%, and one noted <. 30%. Six patients had no change in AED burden. Vagus nerve stimulation lead revision should be considered a safe option for patients with VNS lead failure and medically intractable epilepsy.",

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AU - Raffa, Scott J.

AU - Benbadis, Selim R.

AU - Vale, Fernando L.

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AB - We present, to our knowledge, the first published analysis of vagus nerve stimulation (VNS) lead revisions to incorporate quality of life, clinical response, and antiepileptic drug (AED) burden in postrevision clinical outcomes. Ten patients were followed and had no postoperative complications. Seven patients had improvement in quality of life, and three experienced no change. Eight patients noted a restoration of clinical response comparable with initial VNS implantation. Seven patients reported 30-60% improvement in seizure reduction, two experienced >. 60%, and one noted <. 30%. Six patients had no change in AED burden. Vagus nerve stimulation lead revision should be considered a safe option for patients with VNS lead failure and medically intractable epilepsy.

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KW - Seizure disorder

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Lead revision surgery for vagus nerve stimulation in epilepsy: Outcomes and efficacy

Abstract

Keywords

ASJC Scopus subject areas

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