TY - JOUR
T1 - Low 25-hydroxyvitamin D levels in adolescents
T2 - Race, season, adiposity, physical activity, and fitness
AU - Dong, Yanbin
AU - Pollock, Norman K.
AU - Stallmann-Jorgensen, Inger Susanne
AU - Gutin, Bernard
AU - Lan, Ling
AU - Chen, Tai C.
AU - Keeton, Daniel
AU - Petty, Karen
AU - Holick, Michael F.
AU - Zhu, Haidong
PY - 2010/6
Y1 - 2010/6
N2 - OBJECTIVES: The objectives were to characterize the vitamin D status of black and white adolescents residing in the southeastern United States (latitude: ∼33°N) and to investigate relationships with adiposity. METHODS: Plasma 25-hydroxyvitamin D levels were measured with liquid chromatography-tandem mass spectroscopy for 559 adolescents 14 to 18 years of age (45% black and 49% female). Fat tissues, physical activity, and cardiovascular fitness also were measured. RESULTS: The overall prevalences of vitamin D insufficiency (<75 nmol/L) and deficiency (≥50 nmol/L) were 56.4% and 28.8%, respectively. Black versus white subjects had significantly lower plasma 25-hydroxyvitamin D levels in every season (winter, 35.9 ± 2.5 vs 77.4 ± 2.7 nmol/L; spring, 46.4±3.5 vs 101.3±3.5 nmol/L; summer, 50.7±4.0 vs 104.3 ± 4.0 nmol/L; autumn, 54.4 ± 4.0 vs 96.8 ± 2.7 nmol/L). With adjustment for age, gender, race, season, height, and sexual maturation, there were significant inverse correlations between 25-hydroxyvitamin D levels and all adiposity measurements, including BMI percentile (P=.02), waist circumference (P<.01), total fat mass (P< .01), percentage of body fat (P < .01), visceral adipose tissue (P = .015), and subcutaneous abdominal adipose tissue (P < .039). There were significant positive associations between 25-hydroxyvitamin D levels and vigorous physical activity (P < .01) and cardiovascular fitness (P = .025). CONCLUSIONS: Low vitamin D status is prevalent among adolescents living in a year-round sunny climate, particularly among black youths. The relationships between 25-hydroxyvitamin D levels, adiposity, physical activity, and fitness seem to be present in adolescence.
AB - OBJECTIVES: The objectives were to characterize the vitamin D status of black and white adolescents residing in the southeastern United States (latitude: ∼33°N) and to investigate relationships with adiposity. METHODS: Plasma 25-hydroxyvitamin D levels were measured with liquid chromatography-tandem mass spectroscopy for 559 adolescents 14 to 18 years of age (45% black and 49% female). Fat tissues, physical activity, and cardiovascular fitness also were measured. RESULTS: The overall prevalences of vitamin D insufficiency (<75 nmol/L) and deficiency (≥50 nmol/L) were 56.4% and 28.8%, respectively. Black versus white subjects had significantly lower plasma 25-hydroxyvitamin D levels in every season (winter, 35.9 ± 2.5 vs 77.4 ± 2.7 nmol/L; spring, 46.4±3.5 vs 101.3±3.5 nmol/L; summer, 50.7±4.0 vs 104.3 ± 4.0 nmol/L; autumn, 54.4 ± 4.0 vs 96.8 ± 2.7 nmol/L). With adjustment for age, gender, race, season, height, and sexual maturation, there were significant inverse correlations between 25-hydroxyvitamin D levels and all adiposity measurements, including BMI percentile (P=.02), waist circumference (P<.01), total fat mass (P< .01), percentage of body fat (P < .01), visceral adipose tissue (P = .015), and subcutaneous abdominal adipose tissue (P < .039). There were significant positive associations between 25-hydroxyvitamin D levels and vigorous physical activity (P < .01) and cardiovascular fitness (P = .025). CONCLUSIONS: Low vitamin D status is prevalent among adolescents living in a year-round sunny climate, particularly among black youths. The relationships between 25-hydroxyvitamin D levels, adiposity, physical activity, and fitness seem to be present in adolescence.
KW - 25-hydroxyvitamin D
KW - Adiposity
KW - Adolescents
KW - Fitness
KW - Physical activity
KW - Race
KW - Vitamin D deficiency
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U2 - 10.1542/peds.2009-2055
DO - 10.1542/peds.2009-2055
M3 - Article
C2 - 20439594
AN - SCOPUS:77953047816
SN - 0031-4005
VL - 125
SP - 1104
EP - 1111
JO - Pediatrics
JF - Pediatrics
IS - 6
ER -