TY - JOUR
T1 - Modeling dynamic functional connectivity with latent factor Gaussian processes
AU - Li, Lingge
AU - Pluta, Dustin
AU - Shahbaba, Babak
AU - Fortin, Norbert
AU - Ombao, Hernando
AU - Baldi, Pierre
N1 - Publisher Copyright:
© 2019 Neural information processing systems foundation. All rights reserved.
PY - 2019
Y1 - 2019
N2 - Dynamic functional connectivity, as measured by the time-varying covariance of neurological signals, is believed to play an important role in many aspects of cognition. While many methods have been proposed, reliably establishing the presence and characteristics of brain connectivity is challenging due to the high dimensionality and noisiness of neuroimaging data. We present a latent factor Gaussian process model which addresses these challenges by learning a parsimonious representation of connectivity dynamics. The proposed model naturally allows for inference and visualization of connectivity dynamics. As an illustration of the scientific utility of the model, application to a data set of rat local field potential activity recorded during a complex non-spatial memory task provides evidence of stimuli differentiation.
AB - Dynamic functional connectivity, as measured by the time-varying covariance of neurological signals, is believed to play an important role in many aspects of cognition. While many methods have been proposed, reliably establishing the presence and characteristics of brain connectivity is challenging due to the high dimensionality and noisiness of neuroimaging data. We present a latent factor Gaussian process model which addresses these challenges by learning a parsimonious representation of connectivity dynamics. The proposed model naturally allows for inference and visualization of connectivity dynamics. As an illustration of the scientific utility of the model, application to a data set of rat local field potential activity recorded during a complex non-spatial memory task provides evidence of stimuli differentiation.
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M3 - Conference article
AN - SCOPUS:85090169808
SN - 1049-5258
VL - 32
JO - Advances in Neural Information Processing Systems
JF - Advances in Neural Information Processing Systems
T2 - 33rd Annual Conference on Neural Information Processing Systems, NeurIPS 2019
Y2 - 8 December 2019 through 14 December 2019
ER -