Multiple myeloma associated with lactic acidosis

Celalettin Ustun; Pamela Fall; Harold M. Szerlip; Anand Jillella; Linda Henricks; Russell Burgess; Paul Dainer

doi:10.1080/1042819021000040116

Multiple myeloma associated with lactic acidosis

Celalettin Ustun, Pamela Fall, Harold M. Szerlip, Anand Jillella, Linda Henricks, Russell Burgess, Paul Dainer

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Type B lactic acidosis is rare among patients with malignant diseases. To date only one case report has documented lactic acidosis occurring in a patient with multiple myeloma (MM). Our patient, a 55-year-old black man, was diagnosed with stage IIIA immunoglobulin G-kappa (IgG-κ) MM in September 1995. He was found to have severe lactic acidosis at the time of second relapse. During the terminal phase of his disease, he required multiple hospitalizations for management of lactic acidosis and other complications of his MM. No other cause of his elevated lactate levels was identified. Although type B lactic acidosis may more commonly occur in patients with leukemia or lymphoma, it may rarely present in patients with rapidly progressive and refractory MM.

Original language	English (US)
Pages (from-to)	2395-2397
Number of pages	3
Journal	Leukemia and Lymphoma
Volume	43
Issue number	12
DOIs	https://doi.org/10.1080/1042819021000040116
State	Published - Dec 1 2002

Keywords

Immunoglobulin
Lactate metabolism
Lactic acidosis
Multiple myeloma

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/1042819021000040116

Cite this

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abstract = "Type B lactic acidosis is rare among patients with malignant diseases. To date only one case report has documented lactic acidosis occurring in a patient with multiple myeloma (MM). Our patient, a 55-year-old black man, was diagnosed with stage IIIA immunoglobulin G-kappa (IgG-κ) MM in September 1995. He was found to have severe lactic acidosis at the time of second relapse. During the terminal phase of his disease, he required multiple hospitalizations for management of lactic acidosis and other complications of his MM. No other cause of his elevated lactate levels was identified. Although type B lactic acidosis may more commonly occur in patients with leukemia or lymphoma, it may rarely present in patients with rapidly progressive and refractory MM.",

keywords = "Immunoglobulin, Lactate metabolism, Lactic acidosis, Multiple myeloma",

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AU - Ustun, Celalettin

AU - Fall, Pamela

AU - Szerlip, Harold M.

AU - Jillella, Anand

AU - Henricks, Linda

AU - Burgess, Russell

AU - Dainer, Paul

PY - 2002/12/1

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N2 - Type B lactic acidosis is rare among patients with malignant diseases. To date only one case report has documented lactic acidosis occurring in a patient with multiple myeloma (MM). Our patient, a 55-year-old black man, was diagnosed with stage IIIA immunoglobulin G-kappa (IgG-κ) MM in September 1995. He was found to have severe lactic acidosis at the time of second relapse. During the terminal phase of his disease, he required multiple hospitalizations for management of lactic acidosis and other complications of his MM. No other cause of his elevated lactate levels was identified. Although type B lactic acidosis may more commonly occur in patients with leukemia or lymphoma, it may rarely present in patients with rapidly progressive and refractory MM.

AB - Type B lactic acidosis is rare among patients with malignant diseases. To date only one case report has documented lactic acidosis occurring in a patient with multiple myeloma (MM). Our patient, a 55-year-old black man, was diagnosed with stage IIIA immunoglobulin G-kappa (IgG-κ) MM in September 1995. He was found to have severe lactic acidosis at the time of second relapse. During the terminal phase of his disease, he required multiple hospitalizations for management of lactic acidosis and other complications of his MM. No other cause of his elevated lactate levels was identified. Although type B lactic acidosis may more commonly occur in patients with leukemia or lymphoma, it may rarely present in patients with rapidly progressive and refractory MM.

KW - Immunoglobulin

KW - Lactate metabolism

KW - Lactic acidosis

KW - Multiple myeloma

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Multiple myeloma associated with lactic acidosis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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