Abstract
Acute Disseminated Encephalomyelitis (ADEM) is a monophasic demyelinating disease most often triggered by infection or immunization, though associations with malignancy and stem cell transplant have been described. We described the case of a four-year-old boy with new-onset neurological symptoms associated with ADEM, acute leukemia, and equivocal evidence of Mycoplasma pneumoniae infection. He responded to a short course of antibiotics and chemotherapy for B cell acute lymphoblastic leukemia (B-ALL) that included a prolonged course of high dose steroids with immunosuppressive therapy. This case illustrated a possible association between paraneoplastic ADEM and leukemia in pediatric patients.
Original language | English (US) |
---|---|
Pages (from-to) | 161-165 |
Number of pages | 5 |
Journal | Iranian Journal of Pediatric Hematology and Oncology |
Volume | 13 |
Issue number | 2 |
DOIs | |
State | Published - 2023 |
Externally published | Yes |
Keywords
- Encephalomyelitis
- Leukemia
- Paraneoplastic
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Hematology
- Oncology