Perforin and Fas cytolytic pathways coordinately shape the selection and diversity of CD8⁺-T-cell escape variants of influenza virus

Keyphrases

• T Cells 100%
• Perforin 100%
• CD8+ 100%
• Influenza Virus 100%
• Cytolytic 100%
• Escape Variants 100%
• Cytotoxic T Cells 85%
• Viral 42%
• Host Immune Response 28%
• Subtype Diversity 28%
• Transgenic 14%
• Mutation Rate 14%
• Cytotoxic CD8+ T Cells 14%
• Virus 14%
• Virus-specific 14%
• Gene-deficient Mice 14%
• Specific T Cells 14%
• Vaccine Development 14%
• T Cell Receptor 14%
• Antigenic Variation 14%
• Respiratory Tract 14%
• Neutralizing Antibodies 14%
• Mice Transgenic 14%
• Influenza-like Illness 14%
• FasL 14%
• Surface Glycoprotein 14%
• Protective Immunity 14%
• Mutant Virus 14%
• Antigenic Evolution 14%
• Viral Clearance 14%
• Transmissibility 14%
• New Strain 14%
• Cytotoxic Pathways 14%
• Viral Control 14%
• Prior Infection 14%
• Viral Escape 14%
• Granzyme 14%
• Antigenic Change 14%
• Fas Pathway 14%
• Prior Vaccination 14%
• Virus Emergence 14%

Immunology and Microbiology

• Cytotoxic T-Cell 100%
• Perforin 100%
• Cytotoxic T Cell 100%
• Influenza Virus 100%
• Mouse 57%
• Infectious Agent 14%
• Mutation Rate 14%
• Vaccination Policy 14%
• Vaccine Efficacy 14%
• Viral Disease 14%
• T Cell Receptor 14%
• Neutralizing Antibody 14%
• Glycoprotein 14%
• CD8 14%
• Transgenics 14%
• Surface Property 14%
• Transgenic Mouse 14%
• Antigenic Variation 14%
• Host Immune Response 14%
• Granzyme 14%
• Viral Clearance 14%