Plasmapheresis for fulminant meningococcemia

M. S. Drapkin, J. S. Wisch, J. A. Gelfand, J. G. Cannon, C. A. Dinarello

Research output: Contribution to journalArticlepeer-review

51 Scopus citations


Fulminant meningococcemia remains one of the most frightening and lethal of infections, capable of resulting in death within hours. Reports of the use of plasmapheresis in a few patients with the syndrome prompted us to utilize that technique recently in a severely ill patient. Improvement correlated with dropping plasma concentrations of tumor necrosis factor alpha (TNF) and of interleukin 1-beta (IL-1), suggesting a possible rationale for such treatment.

Original languageEnglish (US)
Pages (from-to)399-400
Number of pages2
JournalPediatric Infectious Disease Journal
Issue number6
StatePublished - Jan 1 1989

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases


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