Prader-Willi syndrome: Periodontal-prosthodontic rehabilitation in an adult patient

Justin Mackert, Brian Mears, D. J. Pannu, Mira Ghaly, Jimmy Londono, Ahmed R. El-Awady, Mark E. Peacock

Research output: Contribution to journalArticlepeer-review


Introduction: Prader-Willi syndrome (PWS) is a rare genetic multisystemic disease that is the most common inherited cause of severe childhood obesity. PWS patients are prone to significant oral and systemic health issues that detrimentally affect quality of life and decrease longevity. This report documents full-mouth pre-prosthetic surgical and restorative care in an adult PWS patient. Case Report: The patient, a 29-year-old male, presented to the clinic accompanied by his guardians (parents) with the chief complaint that “My Teeth are breaking down and I would like to get them fixed”. Periodontal and prosthetic comprehensive clinical and radiographic exams revealed a severely worn dentition, deep anterior overbite, altered passive eruption with generalized biofilm-induced gingivitis, and altered occlusal vertical dimension. Full mouth crown lengthening surgery combined with full mouth prosthodontic reconstruction was performed under parenteral sedation and local anesthesia. Completion of treatment was successful, and the patient was placed on a 3-month periodontal maintenance interval. Discussion: Full mouth periodontal surgical and prosthodontic reconstruction on a PWS patient has not previously been reported in the literature. This case underscores the potential need for complex dental care in patients with this syndrome.

Original languageEnglish (US)
Pages (from-to)486-491
Number of pages6
JournalSpecial Care in Dentistry
Issue number4
StatePublished - Jul 1 2023


  • Prader-Willi syndrome
  • medically compromised patient
  • special care dentistry

ASJC Scopus subject areas

  • Dentistry(all)


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