Predictors and Moderators of Sexually Related Distress in Women with Persistent Genital Arousal Disorder

Lisa Squibb, Lara Stepleman, Irwin Goldstein, Michael Sand, Brian Zamboni

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


The degree of general distress reported by women with Persistent Genital Arousal Disorder (PGAD) varies greatly, which might relate to their level of anxiety or depression. A variety of medical problems also has been associated with PGAD symptoms. The current study sought to determine the most significant predictor of sexually related distress and examine possible moderators. Participants were 51 women who met the criteria for PGAD and completed an online survey. Hierarchical regression determined depression significantly predicted sexually related distress, but anxiety and stress measures did not. Erotophobia and perceived partner support did not moderate the relationship between depression and sexually related distress. Greater numbers of concomitant medical diagnoses were significantly correlated with sexually related distress. The results indicate that PGAD is experienced by women as sexually distressing. As we continue to learn more about PGAD, a biopsychosocial treatment approach to PGAD, including psychotherapy would seem warranted.

Original languageEnglish (US)
Pages (from-to)426-438
Number of pages13
JournalInternational Journal of Sexual Health
Issue number4
StatePublished - Oct 2 2019


  • PGAD
  • anxiety
  • depression
  • erotophobia
  • sexual distress
  • stress

ASJC Scopus subject areas

  • Gender Studies
  • Social Psychology
  • Reproductive Medicine
  • Dermatology
  • Public Health, Environmental and Occupational Health


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