Quinidine-induced thrombocytopenia successfully treated with plasma exchange

T. H. Guthrie, C. W. Pallas, J. E. Squires

Research output: Contribution to journalArticlepeer-review


A 66-year-old woman had significant cervical, oral, and gastrointestinal bleeding associated with quindine-induced immune thrombocytopenia. No response to discontinuance of quinidine, high dose steroids, or platelet transfusion was noted after three days of observation. A single plasma exchange induced immediate cessation of bleeding and rapid restoration of a normal platelet count. Plasma exchange would appear to warrant further exploration in the management of drug-induced thrombocytopenia when the offending drug is heavily bound to plasma proteins.

Original languageEnglish (US)
Pages (from-to)361-363
Number of pages3
JournalPlasma Therapy and Transfusion Technology
Issue number3
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Immunology
  • Hematology


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