TY - JOUR
T1 - Relations of adiposity and effects of training on the left ventricle in obese youths
AU - Humphries, Matthew C.
AU - Gutin, Bernard
AU - Barbeau, Paule
AU - Vemulapalli, Sarita
AU - Allison, Jerry
AU - Owens, Scott
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2002/9
Y1 - 2002/9
N2 - Purpose: 1) To determine the relations of left ventricular (LV) structure and function to total body composition, visceral adipose tissue (VAT), and hemodynamics in obese children; 2) to determine the effects of 4-month of physical training (PT) on LV structure and function and hemodynamics; and 3) to explore determinants of individual variability in response to PT. Methods: Measurements included LV structure/function with echocardiography, total body composition with dual-energy x-ray absorptiometry. VAT with magnetic resonance imaging (MRI), and resting and exercising hemodynamics with a Dinamap monitor and Doppler-echocardiography. Youths were randomly assigned to engage in PT for the first or second 4-month periods of the 8-month intervention period. Results: Correlation and regression at baseline showed that elevated LV mass was associated with excess general and visceral adiposity, and elevated cardiac output. Although the PT had favorable effects on percent body fat and VAT, no significant changes were found in LV or hemodynamic variables. Over the 4-month period of the PT intervention, those who increased the most in VAT tended to increase the most in LV mass. Conclusion: General and visceral adiposity were associated with elevated LV mass. However, no evidence was provided that 4 months of PT had a significant effect on LV or hemodynamic variables.
AB - Purpose: 1) To determine the relations of left ventricular (LV) structure and function to total body composition, visceral adipose tissue (VAT), and hemodynamics in obese children; 2) to determine the effects of 4-month of physical training (PT) on LV structure and function and hemodynamics; and 3) to explore determinants of individual variability in response to PT. Methods: Measurements included LV structure/function with echocardiography, total body composition with dual-energy x-ray absorptiometry. VAT with magnetic resonance imaging (MRI), and resting and exercising hemodynamics with a Dinamap monitor and Doppler-echocardiography. Youths were randomly assigned to engage in PT for the first or second 4-month periods of the 8-month intervention period. Results: Correlation and regression at baseline showed that elevated LV mass was associated with excess general and visceral adiposity, and elevated cardiac output. Although the PT had favorable effects on percent body fat and VAT, no significant changes were found in LV or hemodynamic variables. Over the 4-month period of the PT intervention, those who increased the most in VAT tended to increase the most in LV mass. Conclusion: General and visceral adiposity were associated with elevated LV mass. However, no evidence was provided that 4 months of PT had a significant effect on LV or hemodynamic variables.
KW - Body fat
KW - Left ventricular structure
KW - Pediatrics
KW - Physical training
KW - Visceral adipose tissue
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U2 - 10.1097/00005768-200209000-00005
DO - 10.1097/00005768-200209000-00005
M3 - Article
C2 - 12218734
AN - SCOPUS:0036713711
SN - 0195-9131
VL - 34
SP - 1428
EP - 1435
JO - Medicine and Science in Sports and Exercise
JF - Medicine and Science in Sports and Exercise
IS - 9
ER -