Risk factors associated with high prevalence rates of hepatitis C infection in Egypt

Celeste Reker, K. M. Islam

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Introduction: Egypt has the highest reported prevalence of hepatitis C virus (HCV) globally. Until now, no systematic review has been conducted to understand risk factors associated with these high prevalence rates of HCV. This study attempted to identify the various HCV risk factors in Egypt responsible for the high incidence and prevalence rates. Methods: Using systematic literature review methods, we searched databases for eligible manuscripts, selecting cohort and case-control studies published in English. Peer-reviewed papers published between 2008 and February 2013 were included. A total of 11 articles met the study selection criteria. Results: The most examined risk factors found during our review analysis were surgery, transfusion, and age (64-82% of total articles; n = 11). Multiple risk factors held significant association with HCV infection in the included research. Conclusions: Based on this review, the main HCV risk factor categories are unsafe medical practices and familial risk factors. Improving medical safety and encouraging familial education on HCV may help reduce the incidence of the disease. Most risk factors for HCV transmission in Egypt are healthcare-associated. Primary prevention of HCV infection remains important to reduce HCV transmission. Further research should also focus on risk factor dynamics of HCV in Egypt to reduce transmission and HCV disease burden.

Original languageEnglish (US)
Pages (from-to)104-106
Number of pages3
JournalInternational Journal of Infectious Diseases
StatePublished - Aug 2014
Externally publishedYes


  • Egypt
  • Hepatitis C
  • Risk factor

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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