Salivary gland neoplasms as a late consequence of head and neck irradiation

A. B. Schneider; M. J. Favus; M. E. Stachura; M. J. Arnold; L. A. Frohman

doi:10.7326/0003-4819-87-2-160

Salivary gland neoplasms as a late consequence of head and neck irradiation

A. B. Schneider, M. J. Favus, M. E. Stachura, M. J. Arnold, L. A. Frohman

Endocrinology

Research output: Contribution to journal › Article › peer-review

100 Scopus citations

Abstract

An increased occurrence of salivary tumors was observed in 1922 patients who received radiation to the tonsils and nasopharynx. Twenty seven tumors, 19 benign and 8 malignant, were found in this group as compared with an expected 0.2 malignant < 1 benign tumor. The latent period between the initial radiation treatment and diagnosis ranged from 7 to 32 yr. After the first 15 yr the incidence (77 cases/10⁵ subjects/yr) has remained constant and shows no indication of declining. Continued observation for salivary gland tumors is therefore indicated for subjects who received childhood irradiation.

Original language	English (US)
Pages (from-to)	160-164
Number of pages	5
Journal	Unknown Journal
Volume	87
Issue number	2
DOIs	https://doi.org/10.7326/0003-4819-87-2-160
State	Published - Jan 1 1977

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Internal Medicine

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title = "Salivary gland neoplasms as a late consequence of head and neck irradiation",

abstract = "An increased occurrence of salivary tumors was observed in 1922 patients who received radiation to the tonsils and nasopharynx. Twenty seven tumors, 19 benign and 8 malignant, were found in this group as compared with an expected 0.2 malignant < 1 benign tumor. The latent period between the initial radiation treatment and diagnosis ranged from 7 to 32 yr. After the first 15 yr the incidence (77 cases/105 subjects/yr) has remained constant and shows no indication of declining. Continued observation for salivary gland tumors is therefore indicated for subjects who received childhood irradiation.",

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AU - Favus, M. J.

AU - Stachura, M. E.

AU - Arnold, M. J.

AU - Frohman, L. A.

PY - 1977/1/1

Y1 - 1977/1/1

N2 - An increased occurrence of salivary tumors was observed in 1922 patients who received radiation to the tonsils and nasopharynx. Twenty seven tumors, 19 benign and 8 malignant, were found in this group as compared with an expected 0.2 malignant < 1 benign tumor. The latent period between the initial radiation treatment and diagnosis ranged from 7 to 32 yr. After the first 15 yr the incidence (77 cases/105 subjects/yr) has remained constant and shows no indication of declining. Continued observation for salivary gland tumors is therefore indicated for subjects who received childhood irradiation.

AB - An increased occurrence of salivary tumors was observed in 1922 patients who received radiation to the tonsils and nasopharynx. Twenty seven tumors, 19 benign and 8 malignant, were found in this group as compared with an expected 0.2 malignant < 1 benign tumor. The latent period between the initial radiation treatment and diagnosis ranged from 7 to 32 yr. After the first 15 yr the incidence (77 cases/105 subjects/yr) has remained constant and shows no indication of declining. Continued observation for salivary gland tumors is therefore indicated for subjects who received childhood irradiation.

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Salivary gland neoplasms as a late consequence of head and neck irradiation

Abstract

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