Sequencing chromosomal abnormalities reveals neurodevelopmental loci that confer risk across diagnostic boundaries

Keyphrases

• Neurodevelopmental 100%
• Autism 100%
• Chromosomal Abnormalities 100%
• Diagnostic Boundaries 100%
• Balanced Chromosomal Abnormalities 66%
• Neurodevelopmental Disorders 66%
• Phenotypic Outcome 33%
• Schizophrenia 33%
• Copy number Variation 33%
• Genome-wide Association Study 33%
• Psychiatric Disorders 33%
• Transcription Factor 4 (TCF4) 33%
• Neurodevelopment 33%
• Late-onset 33%
• Gene Disruption 33%
• Risk Allele 33%
• Risk Loci 33%
• Life Stages 33%
• ZNF804A 33%
• ZNF507 33%
• Microdeletion Syndrome 33%
• Neurodevelopmental Genes 33%
• CHD8 33%
• Mutational Mechanism 33%
• ANK3 33%
• SATB2 33%
• Polygenic Risk Model 33%
• FOXP1 33%
• CDKL5 33%
• GRIN2B 33%
• Phosphodiesterase 10A (PDE10A) 33%
• Kirrel3 33%
• Polygenic Risk 33%
• MBD5 33%
• EHMT1 33%
• AUTS2 33%
• SNRPN 33%

Biochemistry, Genetics and Molecular Biology

• Chromosomal Abnormalities 100%
• Allele 33%
• Genome-Wide Association Study 33%
• Nerve Cell Differentiation 33%
• Gene Disruption 33%
• TCF4 33%
• EHMT1 33%
• Microdeletion Syndrome 33%
• ANK3 33%
• FOXP1 33%
• SATB2 33%
• CDKL5 33%
• GRIN2B 33%
• CHD8 33%
• PDE10A 33%

Neuroscience

• Pervasive Developmental Disorder 100%
• Dementia Praecox 33%
• Nerve Cell Differentiation 33%
• Genome-Wide Association Study 33%
• Gene Disruption 33%
• TCF4 33%
• FOXP1 33%
• GRIN2B 33%
• SATB2 33%
• CDKL5 33%