Sequential activation of JAKs, STATs and xanthine dehydrogenase/oxidase by hypoxia in lung microvascular endothelial cells

Medicine & Life Sciences

• Xanthine Dehydrogenase 100%
• Janus Kinases 86%
• Xanthine Oxidase 80%
• Transducers 67%
• Hypoxia 51%
• Endothelial Cells 48%
• Lung 35%
• Interleukin-6 20%
• alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 19%
• Janus Kinase Inhibitors 9%
• Phosphorylation 9%
• Cytokines 8%
• SB 203580 8%
• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 7%
• Antibodies 7%
• p38 Mitogen-Activated Protein Kinases 6%
• Phosphatidylinositol 3-Kinase 6%
• Transcriptional Activation 5%
• DNA 3%
• Wounds and Injuries 3%

Chemical Compounds

• Xanthine 73%
• LY294002 60%
• Phosphatidylinositol 3 Kinase Inhibitor 56%
• Phosphotransferase Inhibitor 41%
• Effector 35%