Spatial regulation of translation through RNA localization

Graydon B. Gonsalvez; Roy M. Long

doi:10.3410/B4-16

Spatial regulation of translation through RNA localization

Graydon B. Gonsalvez, Roy M. Long

Cellular Biology and Anatomy

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

Abstract

RNA localization is a mechanism to post-transcriptionally regulate gene expression. Eukaryotic organisms ranging from fungi to mammals localize mRNAs to spatially restrict synthesis of specific proteins to distinct regions of the cytoplasm. In this review, we provide a general summary of RNA localization pathways in Saccharomyces cerevisiae, Xenopus, Drosophila and mammalian neurons.

Original language	English (US)
Article number	16
Journal	F1000 Biology Reports
Volume	4
Issue number	1
DOIs	https://doi.org/10.3410/B4-16
State	Published - 2012

ASJC Scopus subject areas

Neuroscience(all)
Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)
Pharmacology, Toxicology and Pharmaceutics(all)

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10.3410/B4-16

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abstract = "RNA localization is a mechanism to post-transcriptionally regulate gene expression. Eukaryotic organisms ranging from fungi to mammals localize mRNAs to spatially restrict synthesis of specific proteins to distinct regions of the cytoplasm. In this review, we provide a general summary of RNA localization pathways in Saccharomyces cerevisiae, Xenopus, Drosophila and mammalian neurons.",

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AB - RNA localization is a mechanism to post-transcriptionally regulate gene expression. Eukaryotic organisms ranging from fungi to mammals localize mRNAs to spatially restrict synthesis of specific proteins to distinct regions of the cytoplasm. In this review, we provide a general summary of RNA localization pathways in Saccharomyces cerevisiae, Xenopus, Drosophila and mammalian neurons.

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Spatial regulation of translation through RNA localization

Abstract

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