Spiroindole-containing compounds bearing phosphonate group of potential M^pro-SARS-CoV-2 inhibitory properties

Keyphrases

• Inhibitory Properties 100%
• Spiroindolenine 100%
• SARS-CoV-2 Mpro 100%
• Compound Bearing 100%
• Phosphonate Groups 100%
• Selectivity Index 50%
• Phosphonates 50%
• Anti-SARS-CoV-2 50%
• Viral 25%
• Mode of Action 25%
• Cycloaddition 25%
• Pyrrolidine 25%
• 4-Piperidones 25%
• Azomethine Ylide 25%
• Excellent Yields 25%
• Molecular Docking Studies 25%
• Dispiro 25%
• Isatin 25%
• Sarcosine 25%
• Single-crystal X-ray Study 25%
• Ylidenes 25%
• Indoline 25%
• Vero E6 Cells 25%
• Microwave-assisted Reaction 25%
• Mpro 25%
• Piperidin 25%

Chemistry

• Phosphonate 100%
• Pyrrolidine 50%
• Piperidones 50%
• Azomethine Ylide 50%
• Single Crystalline Solid 50%
• Sarcosine 50%
• Isatin 50%
• Indolines 50%
• Phosphonate(1-) 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Phosphonate 100%
• SARS Coronavirus 100%
• Piperidone Derivative 20%
• Pyrrolidine Derivative 20%
• Isatin 20%
• Sarcosine 20%
• Azomethine Ylide 20%