Study of dose enhancement effects in the vicinity of high Z atoms with Geant4 Monte Carlo simulation

Ke Huang; Kaiguo Yan; Yan Yu

doi:10.1109/BMEI.2010.5639270

Study of dose enhancement effects in the vicinity of high Z atoms with Geant4 Monte Carlo simulation

Ke Huang, Kaiguo Yan, Yan Yu

Medical Laboratory, Imaging and Radiologic Sciences

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Dose enhancements in the vicinity of different high Z (HZ) materials in radiation therapy (RT) are studied by several groups. In this work, extensive and systematic Monte Carlo (MC) studies were performed with Geant4 toolkit focusing on factors that influence the dose enhancements, including the atomic number of HZ materials, the concentration of the HZ material, and the X-ray energies. Gold (Au), Platinum (Pt), Gadolinium (Gd), and Iodine (I) are used in the study. A new method has been implemented to determine the individual contributions from pair production, Compton scattering and the photoelectric effect to the total dose. The dose enhancement ratios (DERs) and their contributions to the overall dose deposition are calculated for these processes. It is also shown in the study that with fixed X-ray energy and molar concentration, the DERs for these HZ materials are approximately linear proportional to their Z number. The DER increases linearly with HZ concentration; however, the slope of the increase depends on the X-ray energies. Analysis of the DERs from different processes reveals an interesting phenomenon: although the contribution from the photoelectric effect to the overall dose enhancement for X-rays in the MeV range is low, being normally less than 3%, the DER for the photoelectric effect from MeV X-rays are higher than that from X-rays in keV range.

Original language	English (US)
Title of host publication	Proceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010
Pages	1260-1264
Number of pages	5
Volume	3
DOIs	https://doi.org/10.1109/BMEI.2010.5639270
State	Published - Dec 1 2010
Event	3rd International Conference on BioMedical Engineering and Informatics, BMEI 2010 - Yantai, China Duration: Oct 16 2010 → Oct 18 2010

Other

Other	3rd International Conference on BioMedical Engineering and Informatics, BMEI 2010
Country/Territory	China
City	Yantai
Period	10/16/10 → 10/18/10

Keywords

Contribution from processes
Dose enhancement
Gold
High Z
Radiation therapy
X-rays

ASJC Scopus subject areas

Biomedical Engineering
Health Informatics
Health Information Management

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10.1109/BMEI.2010.5639270

Cite this

Huang, K, Yan, K & Yu, Y 2010, Study of dose enhancement effects in the vicinity of high Z atoms with Geant4 Monte Carlo simulation. in Proceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010. vol. 3, 5639270, pp. 1260-1264, 3rd International Conference on BioMedical Engineering and Informatics, BMEI 2010, Yantai, China, 10/16/10. https://doi.org/10.1109/BMEI.2010.5639270

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abstract = "Dose enhancements in the vicinity of different high Z (HZ) materials in radiation therapy (RT) are studied by several groups. In this work, extensive and systematic Monte Carlo (MC) studies were performed with Geant4 toolkit focusing on factors that influence the dose enhancements, including the atomic number of HZ materials, the concentration of the HZ material, and the X-ray energies. Gold (Au), Platinum (Pt), Gadolinium (Gd), and Iodine (I) are used in the study. A new method has been implemented to determine the individual contributions from pair production, Compton scattering and the photoelectric effect to the total dose. The dose enhancement ratios (DERs) and their contributions to the overall dose deposition are calculated for these processes. It is also shown in the study that with fixed X-ray energy and molar concentration, the DERs for these HZ materials are approximately linear proportional to their Z number. The DER increases linearly with HZ concentration; however, the slope of the increase depends on the X-ray energies. Analysis of the DERs from different processes reveals an interesting phenomenon: although the contribution from the photoelectric effect to the overall dose enhancement for X-rays in the MeV range is low, being normally less than 3%, the DER for the photoelectric effect from MeV X-rays are higher than that from X-rays in keV range.",

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AB - Dose enhancements in the vicinity of different high Z (HZ) materials in radiation therapy (RT) are studied by several groups. In this work, extensive and systematic Monte Carlo (MC) studies were performed with Geant4 toolkit focusing on factors that influence the dose enhancements, including the atomic number of HZ materials, the concentration of the HZ material, and the X-ray energies. Gold (Au), Platinum (Pt), Gadolinium (Gd), and Iodine (I) are used in the study. A new method has been implemented to determine the individual contributions from pair production, Compton scattering and the photoelectric effect to the total dose. The dose enhancement ratios (DERs) and their contributions to the overall dose deposition are calculated for these processes. It is also shown in the study that with fixed X-ray energy and molar concentration, the DERs for these HZ materials are approximately linear proportional to their Z number. The DER increases linearly with HZ concentration; however, the slope of the increase depends on the X-ray energies. Analysis of the DERs from different processes reveals an interesting phenomenon: although the contribution from the photoelectric effect to the overall dose enhancement for X-rays in the MeV range is low, being normally less than 3%, the DER for the photoelectric effect from MeV X-rays are higher than that from X-rays in keV range.

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Study of dose enhancement effects in the vicinity of high Z atoms with Geant4 Monte Carlo simulation

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