@article{0eaf2ff345d14557be690bbc7f6e6915,
title = "Synthesis, antibacterial properties and 2D-QSAR studies of quinolone-triazole conjugates",
abstract = "A set of 1,2,3-triazole incorporated quinolone antibiotic conjugates 10–15, 17–19 were synthesized via microwave assisted click chemistry technique. Some of the aryl-substituted conjugates 17–19 show promising antibacterial properties against the tested Gram-positive (S. aureus and S. pyogenes) and Gram-negative bacteria (S. typhi) with potency higher than that of the parent antibiotics 1–3. 2D-QSAR modeling supports the observed biological properties.",
keywords = "1,2,3-Triazole, Antibacterial, Conjugate, QSAR, Quinolone",
author = "Faidallah, {Hassan M.} and Girgis, {Adel S.} and Tiwari, {Anand D.} and Honkanadavar, {Hitesh H.} and Thomas, {Sean J.} and Ahmed Samir and Atef Kalmouch and Alamry, {Khalid A.} and Khan, {Khalid A.} and Ibrahim, {Tarek S.} and AL-Mahmoudy, {Amany M.M.} and Asiri, {Abdullah M.} and Panda, {Siva S.}",
note = "Funding Information: This project was funded by the National Plan for Science, Technology and Innovation (MAARIFAH) – King Abdulaziz City for Science and Technology - the Kingdom of Saudi Arabia – award number ( 12-ADV2732-03 ). The authors also, acknowledge with thanks Science and Technology Unit, King Abdulaziz University for technical support. Appendix A Publisher Copyright: {\textcopyright} 2017 Elsevier Masson SAS",
year = "2018",
month = jan,
day = "1",
doi = "10.1016/j.ejmech.2017.10.042",
language = "English (US)",
volume = "143",
pages = "1524--1534",
journal = "CHIM.THER.",
issn = "0223-5234",
publisher = "Elsevier Masson SAS",
}