Synthesis of Novel Heterocycles from 2-Amino-3-cyanomethyl-sulfonyl-4,5-dimethylfuran

Chad E. Stephens, J. Walter Sowell

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


The synthesis and selected reactions of the versatile heterocycle 2-amino-3-cyanomethylsulfonyl-4,5-dimethylfuran is reported. In particular, cyclization reaction of the aminofuran yielded a number of novel furo[3,2-b]thiazine 1,1-dioxides. Additionally, a novel tetracyclic system, namely a pyrrolo[2′,3′:5,6]-[1,4]thiazino[3,2-b]quinoline 4,4-dioxide, is prepared via an intramolecular triple-cyclization in which the furan ring is opened and reclosed as a pyrrole.

Original languageEnglish (US)
Pages (from-to)857-860
Number of pages4
JournalJournal of Heterocyclic Chemistry
Issue number3
StatePublished - 1997
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry


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