The kinetics of estrogen binding to rat α-fetoprotein

Brooks Allen Keel, T. O. Abney

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Fluid obtained from rat fetuses was utilized to characterize the affinity, number of binding sites, and the association and dissociation rate kinetics of the binding of estradiol and estrone to AFP. Statistical analysis demonstrated no differences when the values for the AFP-estradiol interaction were compared with those obtained for the AFP-estrone interaction. These data demonstrate that rat AFP specifically binds estradiol and estrone with a high capacity, high affinity, and similar binding kinetics.

Original languageEnglish (US)
Pages (from-to)503-505
Number of pages3
Issue number5
StatePublished - May 1 1984

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


Dive into the research topics of 'The kinetics of estrogen binding to rat α-fetoprotein'. Together they form a unique fingerprint.

Cite this