Abstract
Stroke is the most common neurologic complication of sickle cell disease. Acute chest syndrome (ACS) is a known risk factor for stroke in this population. Two patients (a 12-year-old boy and a 6-year-old girl) developed acute change of mental status and focal neurologic signs during episodes of ACS. The clinical and radiologic findings were compatible with acute necrotizing encephalitis, a variant of acute demyelinating encephalomyelitis. Patients with acute neurologic deterioration in conjunction with ACS should be evaluated thoroughly for other causes of central nervous system disease including infectious/parainfectious processes as well as stroke.
Original language | English (US) |
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Pages (from-to) | 585-588 |
Number of pages | 4 |
Journal | Journal of Pediatric Hematology/Oncology |
Volume | 24 |
Issue number | 7 |
DOIs | |
State | Published - Oct 2002 |
Keywords
- Acute chest syndrome
- Acute necrotizing encephalopathy
- Mycoplasma pneumonia
- Sickle cell anemia
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Hematology
- Oncology