TY - JOUR
T1 - Various imaging modalities for the detection of salivary gland lesions
T2 - the advantages of tl spet
AU - Arbab, A. S.
AU - Koizumi, K.
AU - Toyama, K.
AU - Nambu, A.
AU - Ichikawa, T.
AU - Arai, T.
AU - Araki, T.
PY - 2000/3
Y1 - 2000/3
N2 - The aim of this study was to compare dual-isotope (Tcm and Tl) SPET imaging with computed tomography (CT) and magnetic resonance imaging (MRI) in the differentiation of various lesions of the major salivary glands. Twenty-two patients underwent dual-isotope SPET imaging, of whom 12 also had CT and 15 also had an MRI study. The uptake ratio and retention index for Tcm and Tl were calculated by drawing regions of interest on the involved and normal glands. Both CT and MRI were interpreted by two radiologists. All malignant tumours were detected by all three modalities. Warthin's tumours were detected by dual-isotope SPET imaging; however, MRI failed to differentiate Warthin's tumour from pleomorphic adenoma. Of 13 other benign tumours, dual-isotope SPET correctly diagnosed 12. Of 16 tumours showing a cold defect on the Tcm images, parametric analysis with Tl gave an accuracy of 94%, whereas CT gave an accuracy of 70-90%. MRI was 73-91% accurate in differentiating between benign (Warthin's) and malignant tumours. We believe that dual-isotope SPET imaging (Tcm and Tl), together with semi-quantitative analysis, is the method of choice for differentiating between various lesions of the major salivary glands.
AB - The aim of this study was to compare dual-isotope (Tcm and Tl) SPET imaging with computed tomography (CT) and magnetic resonance imaging (MRI) in the differentiation of various lesions of the major salivary glands. Twenty-two patients underwent dual-isotope SPET imaging, of whom 12 also had CT and 15 also had an MRI study. The uptake ratio and retention index for Tcm and Tl were calculated by drawing regions of interest on the involved and normal glands. Both CT and MRI were interpreted by two radiologists. All malignant tumours were detected by all three modalities. Warthin's tumours were detected by dual-isotope SPET imaging; however, MRI failed to differentiate Warthin's tumour from pleomorphic adenoma. Of 13 other benign tumours, dual-isotope SPET correctly diagnosed 12. Of 16 tumours showing a cold defect on the Tcm images, parametric analysis with Tl gave an accuracy of 94%, whereas CT gave an accuracy of 70-90%. MRI was 73-91% accurate in differentiating between benign (Warthin's) and malignant tumours. We believe that dual-isotope SPET imaging (Tcm and Tl), together with semi-quantitative analysis, is the method of choice for differentiating between various lesions of the major salivary glands.
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U2 - 10.1097/00006231-200003000-00012
DO - 10.1097/00006231-200003000-00012
M3 - Article
C2 - 10823330
AN - SCOPUS:0034151129
SN - 0143-3636
VL - 21
SP - 277
EP - 284
JO - Nuclear Medicine Communications
JF - Nuclear Medicine Communications
IS - 3
ER -