CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4- amidinophenyl)furan-bis-O-methylamidoxime]
- Michael Zhuo Wang
- , Janelle Y. Saulter
- , Etsuko Usuki
- , Yen Ling Cheung
- , Michael Hall
- , Arlene S. Bridges
- , Greg Loewen
- , Oliver T. Parkinson
- , Chad E. Stephens
- , James L. Allen
- , Darryl C. Zeldin
- , David W. Boykin
- , Richard R. Tidwell
- , Andrew Parkinson
- , Mary F. Paine
- , James Edwin Hall
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